The need for alternatives to DMPA in Sub-Saharan Africa

Authors

  • Vraj Shah McMaster University
  • Eric Chu McMaster University
  • Sachin Davis McMaster University
  • Grace Feng McMaster University

Abstract

Depo-Medroxyprogesterone Acetate (DMPA), or depo, is an injectable hormonal contraceptive, which through studies on sex workers in Sub-Saharan Africa has shown to increase the risk of human immunodeficiency virus (HIV). The uptake results in an increase in diversity within the vaginal microbiome. Furthermore, the increase in diversity is responsible for the decrease in Lactobacilli, leading to increased inflammation and activation of T cells. This is correlated with increased HIV-1 acquisition. Unfortunately, the ease of access to DMPA makes it the most popular contraceptive method in Sub-Saharan Africa. This multimedia submission is meant to educate peers about the issues associated with DMPA in an entertaining way. It also serves the purpose of raising awareness that more research is required along with financial aid in making safer and cheaper alternatives accessible to women of lower social status to protect them from being infected with HIV.

Click here for the video link.

Author Biographies

Vraj Shah, McMaster University

Program: Biomedical Discovery and Commercialization

Department: Biochemistry & Biomedical Sciences

Faculty: Health Sciences

Eric Chu, McMaster University

Program: Biomedical Discovery and Commercialization

Department: Biochemistry & Biomedical Sciences

Faculty: Health Sciences

Sachin Davis, McMaster University

Program: Biomedical Discovery and Commercialization

Department: Biochemistry & Biomedical Sciences

Faculty: Health Sciences

Grace Feng, McMaster University

Program: Biomedical Discovery and Commercialization

Department: Biochemistry & Biomedical Sciences

Faculty: Health Sciences

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Published

2019-04-19