An Arms Race Against Disinfectant Resistance


  • Andriana Tetenych McMaster Univerisity


Antimicrobials, compounds which inhibit or destroy microorganism growth, have revolutionized modern medicine. However, the overuse and misuse of these antimicrobials has led to the emergence of antibiotic and disinfectant resistance through intrinsic and population resistance mechanisms. Single-cell resistance mechanisms include target alteration, inactivation, efflux pumps, and impermeability, while bacterial populations employ biofilms. New technology, such as quantitative polymerase chain reaction, allows for the quantification of this resistance, which is superior to the minimum inhibitory concentration method. Through quantification, prevention strategies, and further research, full comprehension of combatting disinfectant resistance can be acquired.