A Review of Current Treatments for Drug-Resistant Epilepsy via the mTOR Signaling Pathway

Abstract

Epilepsy is a neurological condition that affects 50-300 million people globally and is characterized by abnormal brain activity resulting in the presence and recurrence of seizures.1 Of the affected individuals, 30% exhibit drug-resistant epilepsy (DRE), a form of epilepsy in which current anti-epileptic drugs are ineffective in treating their condition.