Evading Evasion
How Phages get around CRISPR-Cas
DOI:
https://doi.org/10.15173/sciential.v1i1.1910Keywords:
CRISPR-Cas, Anti-CRISPR, Phage, Antimicrobial ResistanceAbstract
The CRISPR-Cas9 system has paved the way for realizing gene-editing, but its main weakness lies in its potential for off-target effects. Studies into phages reveal that they express “anti-CRISPR” proteins which if harnessed, could provide us with the solution to this lack of control.
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