Evading Evasion

How Phages get around CRISPR-Cas

Authors

  • Mostafa Mohammed Elsabagh McMaster University - BHSc - Biomedical Discovery and Commercialization

DOI:

https://doi.org/10.15173/sciential.v1i1.1910

Keywords:

CRISPR-Cas, Anti-CRISPR, Phage, Antimicrobial Resistance

Abstract

The CRISPR-Cas9 system has paved the way for realizing gene-editing, but its main weakness lies in its potential for off-target effects. Studies into phages reveal that they express “anti-CRISPR” proteins which if harnessed, could provide us with the solution to this lack of control.

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Published

2018-11-25

How to Cite

Mohammed Elsabagh, M. (2018). Evading Evasion: How Phages get around CRISPR-Cas. Sciential - McMaster Undergraduate Science Journal, 1(1), 25–27. https://doi.org/10.15173/sciential.v1i1.1910

Issue

Section

Opinion Piece