Evading Evasion

How Phages get around CRISPR-Cas

  • Mostafa Mohammed Elsabagh McMaster University - BHSc - Biomedical Discovery and Commercialization
Keywords: CRISPR-Cas, Anti-CRISPR, Phage, Antimicrobial Resistance


The CRISPR-Cas9 system has paved the way for realizing gene-editing, but its main weakness lies in its potential for off-target effects. Studies into phages reveal that they express “anti-CRISPR” proteins which if harnessed, could provide us with the solution to this lack of control.

How to Cite
Mohammed Elsabagh, M. (2018). Evading Evasion. Sciential - McMaster Undergraduate Science Journal, 1(1), 25-27. Retrieved from https://journals.mcmaster.ca/sciential/article/view/1910
Opinion Piece