Could a Methyl Group Predict Your Risk of Depression?
DOI:
https://doi.org/10.15173/sciential.v1i4.2406Keywords:
MDD, Epigenetics, Biomarker, SerotoninAbstract
Major Depressive Disorder (MDD) is a systemic condition that diminishes the daily quality of life of those affected. There are no current methods that can reliably diagnose depression on a biochemical level. The premise of this work is to report on a potential biochemical marker, DNA methylation of the serotonin transporter gene (5-HTT). This biochemical marker can serve as an indicator of gene expression patterns, ultimately leading to a neurochemical imbalance in affected individuals. Studying this biomarker has the potential to improve diagnostic and therapeutic techniques in the future, and improve the prognosis of those with MDD.
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