Non-Small Cell Lung Carcinoma – A Brief Review and Discussion


  • Bianca Mammarella McMaster
  • Carly Burow McMaster University



Brachytherapy, Lung Cancer, Non-Small Cell, Low-Dose Spiral CT, Cisplatin, Smoking


Lung cancer is the development of cancerous cells within the lung tissue and/or the airway that has potential to further spread. The diagnosis of lung cancer is a multifaceted issue requiring innovative approaches, detection technologies and treatments. Understanding lung cancer’s epidemiology provides insight into lung cancer's high prevalence. As most are diagnosed at further developed stages, recognizing the associated factors will provide a better understanding of how to approach treatment.1Genetic components such as germline mutations and over expression of epidermal growth factor have been analyzed. Advancements in traditional computed tomography (CT) scanning has contributed to an increased survival rate due to the ability to locate tumours in the most dis-crete locations.2 Early detection can occur using a spiral CT scan allowing physicians to perceive the lung cavity from multiple perspectives.3 Early identification of lung cancer is critical in determining the survival of the patient. Treatments for lung cancer that are declared most effective are radiotherapy, chemotherapy, or chemoradiotherapy.4Brachytherapy is an emerging form of radiation therapy that provides radiation in the closest proximity. Cisplatin is the standardized agent, analyzed for its efficiency in the treatment of various stages of lung cancer.5This discussion will explore the epidemiology, detection methods, and one of many available treatment methods to understand therapies and prevention mechanisms for stage three-A NSCLC.




How to Cite

Mammarella, B., & Burow, C. . (2022). Non-Small Cell Lung Carcinoma – A Brief Review and Discussion. Sciential - McMaster Undergraduate Science Journal, (8), 26–33.



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